Skin Re-volumiser


MESOECM is a serum created for intensive regeneration of the damaged extra-cellular matrix and for deactivation inflammation which is responsible for tissue degradation.

Excellence in skin care
  • Description

MESOECM - Skin Re-volumiser

Deep line corrective serum

Improves face oval, skin texture and cohesion – real results

Paraben and fragrance free!

ECM = acronym from: Extra-Cellular Matrix. ECM is a network of non-living tissue that provides support to cells. The term “extra-cellular” literally means “outside the cell” - which explains where the matrix is located.

General product view

MESOECM is a serum created for intensive regeneration of the damaged extra-cellular matrix and for deactivation inflammation which is responsible for tissue degradation.

Active ingredients*

Lipodipeptide Tyrosyl-Arginyl + Rutin + Palmitoyl Oligopeptide + Palmitoyl Tetrapeptide-7 + Phaseolus Extract (Green Bean) + Mannuronate Silanol + 50 kDa Hyaluronic Acid


  • Fully safe. Trusted quality.
  • Paraben Free | Fragrance Free | Alcohol Free | Colourants Free | Allergen Free | Methylisothiazolinone (MIT/MI) Free.
  • Free of formaldehyde (FD) = does not contain DMDM Hydantoin, Diazolidinyl Urea, Imidazolidinyl Urea, Methenamine, Quaternium-15, and Sodium Hydroxymethylglycinate.
  • Free of Epidermal Growth Factors (EGF) which might cause cancerogenic divisions of cells and which might accelerate the mutation of cancer in cells in long-term applications.

Directions for use

  • Daily skin care of face and body
  • Unisex: for women and men, for skin of all types
  • Advanced signs of aging
  • Deep wrinkles and lines
  • Stretch marks
  • Post-acne scars
  • Skin sagginess
  • Lack of skin elasticity and firmness
  • Delicate and sensitive skin
  • Inflammation (one of the causes of extra-cellular matrix degradation)

Efficacy of active ingredients*

  • Rebuilds deficiencies in the structure of the skin (wrinkles, stretch marks, post-acne scars)
  • Stimulates synthesis of collagen, elastin and fibronectin
  • Re-volumises the structure of extra-cellular matrix  (ECM)
  • Provides bio-lifting by re-densifying the skin
  • Improves skin cohesion (anti-sagginess efficacy)
  • Supports extra-cellular matrix in binding tissue together
  • Improves architecture of elastic fibres
  • Improves resistance to gravity
  • Provides visible facial contour lifting and jaw line shaping

Treatments types

  • Mesotherapy
    • electroporation (electrophoresis)
    • ultrasounds (sonophoresis)
    • iontophoresis (+ or –) = no ionisation effect
      (serum does not contain ions so iontophoresis will be neutral)
    • derma-roller / dermapen (max 0,25mm)
      (if you use needles longer than 0,25mm then apply the serum after around
      7-10 minutes from treatment – read micro-needle protocols of use)
  • Oxygen therapy
  • Chromology™ Photodynamic Therapy (PDT)
  • Post abrasion skin care
  • Under algae peel-off beauty mask
  • Under massage cream in manual massages
  • Daily skin care

Application area

All skin areas with visible loss of structure and cohesion of connective tissue (deep furrows, very deep wrinkles, stretch marks, lack of skin firmness and elasticity, saggy skin of face and body).


Water/Aqua, Butylene Glycol, Glycerin, PPG-5-Ceteth-20, Acetyl Dipeptide-1Cetyl Ester, Methylsilanol Mannuronate, Rutin, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Phaseolus Lunatus Extract, Hydrolyzed Hyaluronic Acid, Hydroxyethylcellulose, Sorbitan Laurate, Cetyl Hydroxyethylcellulose, Sodium Polyacrylate Starch, Ethylhexylglycerin, Phenoxyethanol, Lactic Acid, Dipotassium Phosphate.


For external use only. Do not use for needle treatments.

The product is not intended for use with filler injections.

Keep out of the reach of children.


Contraindications: hypersensitivity to any component of the formulation.

Additional info

Can be mixed with CALM Biomimetic Lamellar Cream.

Can be mixed with other serums during one treatment.


Glass ampoules: 10 x 5ml in box


Skin condition improvement visible after single treatment.

Regular application ensures spectacular skin improvement.

* Efficacy of active ingredients confirmed by in vitro and in vivo tests through regular application.

Registered in European Union as Cosmetic Products according to the Cosmetic Directive 76/768/EEC.
Manufactured according to Good Manufacturing Practices (GMP).
Microbiologically and dermatologically tested. | NOT TESTED ON ANIMALS.
Made with the greatest care in the European Union.
Product Safety Data Sheet (PSDS) available on request.